SHIMADZU SCIENTIFIC INSTRUMENTS: Liquid Chromatography Mass Spectrometry
System configuration options include a direct injection system for sample volume-limited analyses for rapid and highly sensitive micro-LCMS analysis without sample loss.
Shimadzu Scientific Instruments (SSI) recently announced the release of the Nexera Mikros microflow liquid chromatography mass spectrometry (LCMS) system. Covering the complete range from microflow to semi-microflow, this system reportedly allows operators to realize high sensitivity with the reliability and ruggedness of high-performance liquid chromatography (HPLC).
System configuration options include a direct injection system for sample volume-limited analyses for rapid and highly sensitive micro-LCMS analysis without sample loss. A trap and elute system is available for analyses with larger injection volumes or when some degree of sample cleanup is desirable. A make-up flow system includes the addition of a post-column make-up flow pump, allowing mobile phase modifiers to be added to ensure the highest ionization efficiency in the MS source.
The Nexera Mikros system’s UF-Link reportedly allows operators to correctly and easily connect any microflow column. The UF-Link ensures a zero-dead volume connection every time. The LC-Mikros pump provides a wide range of flows from micro (0.1 μL/min) to semi-micro (500 μL/min) in both isocratic and gradient elution modes.
According to the company, the SIL-30AC autosampler provides excellent accuracy, reproducibility and ultra-low carry-over. It also offers a trap-and-elute function for higher sample volumes and stronger sample matrices. The newly developed programmable loop cut-off mechanism minimizes system volume and gradient delay. The sample loop is taken off-line after injection, minimizing microflow analysis run times.
For more information, visit www.ssi.shimadzu.com.